7/28/2023 0 Comments Keynote 407![]() This post is updating live… refresh for updates. 28 million copies of Mountain Lion, best selling release of all time Mac is up 100% vs PC up 18% over 5 year growth period paid developers 10 billion (3 times more than all other mobile platforms combined) To conclude, the KEYNOTE-407 trial positioned pembrolizumab-chemotherapy as the new first line treatment of metastatic squamous NSCLC patients with a good PS. 575,000,000 store accounts (more accounts with credit cards than any store online) In patients with previously untreated metastatic nonsquamous NSCLC without EGFR or ALK mutations, the addition of pembrolizumab to standard chemotherapy of pemetrexed and a platinum-based drug. 900,000 apps (93% downloaded each month) Millions of customers come for personal training 6 Million registered developers, 1.5M in last year Below you’ll find a roundup of the stats that Cook shared today including info on retail stores, iPhones and more: Sharing numbers on how its products have been selling and outpacing the competition has become somewhat of a tradition for Apple keynote addresses. Among patients with evaluable data from whole-exome sequencing for evaluation of tTMB (KEYNOTE-189, n 293 KEYNOTE-407, n 312) and matched normal DNA, no association was found between continuous tTMB score and overall survival (OS) or progression-free survival for pembrolizumab-combination (Wald test, one-sided p > 0. Nevertheless, these eligibility criteria can limit the generalizability of results, as patients in real-world oncology practice tend to be older, with more comorbidities than patients treated in clinical trials. Live on stage at Apple’s WWDC keynote presentation this morning, CEO Tim Cook has opened things up with the usual updates on some of the company’s core businesses and accomplishments over the past year. Pembrolizumabchemotherapy was found to have manageable safety in the KEYNOTE-407 China study, and no new safety signals were identified. KEYNOTE-407 had standard trial entry criteria, such as requiring absence of major comorbidities, 7 as is typical for most oncology registration trials.
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